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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a884f66e553cd4ddbbadcc78bf7ee7808babd5d11aeb044d77fe3a1d224a22a' 
  AND token = 'aaXZCAoNCKPGOTHOTCC+p3M/FL5KBMzfy2r56lHcuU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}