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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '415bf226ede95d48149db445d398eb994039011a806ebbf2c0a69cc4e2cd67d1' 
  AND token = 'CPpdDp+arrRaB3vlvvPAS+yUTOYzF4sOrHgdzQ4BAxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}