SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35d245ee34b3e8c02c74d7be285435c021d4d94d6fbd358c8887800244df6b94' 
  AND token = 'h2+8Dn0zSi84RtG1U2x0VDC6GMT7E62XtWUa3wq9Aus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}