SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e6abab1da74d620f44e2fc718740977f3ed3ba3c439aacad273dcbef8e1f115' 
  AND token = '28YW5lnqWNEJofcwEwmwGjes3jefiSynzUXa48kH+To=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}