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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb0f336b85afd1424fb783856742cb9743eabd67ab9388b81f41f81cb6a377a3' 
  AND token = 'OFnFFE1kdUqBEgH1mIFTr0j7YhP3d6PN/1gAA5c2bgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}