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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1e2184367652e8a3dc3269e3d1d93dbd9d4e148925d3002b42143544ebbf40d' 
  AND token = 'GIpOIFxxmE1FE4MzUDJ8WFnfs7DdPL/5+6bWrYtOB18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}