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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '110aa48911d30727e03d5cb091743e2dcaa498901b28ddcec534ae14ca0e156a' 
  AND token = 'xYgl5ft8LQx4e8D3XqcRYx3FoIyalZzqXHWIlc95IMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}