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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca5eb307157aac99a037f32a8af99773da9814cefb800d7dc8bf0583a963f139' 
  AND token = 'NA/37d3KAbaTM9fGn8p/+7CWDr6KMGZibxvrWy5nABo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}