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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2880fc6d62ef6f260bf9ceaf55cc2da31b0a5b508d8c05a971ee5a0b57849cf' 
  AND token = 'X5SrHKmgtumrIjyPd3uHEINBvkrI4WOfu39O4z3RHPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}