SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d80274f3328834f9c4b39f07f3a843a48eb3f28fe032933656b88e5cc36303' 
  AND token = 'GN+qHuRHrGYwBK+pENVD3KMLN/O+VT9zZ91jbLCrjd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}