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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f641ee7749b2feb6869e861ab2e4f9da7b24b1e8d698e7292252439a50ba1cdb' 
  AND token = '/kBjMramVkzZWJ1Zj6wPBkHBXC9R5frDT/k/vwe7oIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}