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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b12d2f17f362e26133f98cf52015fedf991202760aabfce0ce8046f3c09c192' 
  AND token = '1JZzIWbTcBW3JXNWrJCbTBgPHP2nQvL7lp8D0sgbxlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}