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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8397fd83e12a5d7ff9ff4465d8d579f93e8dfe0adefbdd25791f500b53d191c5' 
  AND token = 'a5+bwOUJIBuET/MUr/2uRpov60dzY5K0t2q9DiCrAh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}