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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5537b4a486167f97dc93bb35c4fc843702a1e35fe64b57557385344bfa197ff7' 
  AND token = 'vdz1wyr9lMpncAtTDCo2sOuMFFcwrkJ33bS0uj4/2QE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}