SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35b67bca29cf9ff20ded447adb3cb4b9c79f8cbacec222222ce012d7297af9a1' 
  AND token = 'SwPlkJ4D+8S2X7XFVxuGxMvRDi9loaXCxp2F1gWIE3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}