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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12301b36c9b28d005c98bf4ad0b1e3e6c82f90ce6c665bf4f3e19de663609886' 
  AND token = 'r5C//gUQb3WObkwuDBYdsaBU6RnYKf5NJdwVPS8101I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00099

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}