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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d0a4f5d5dc9b6461f81093b2f214c6c8d1d0ee9301cd208a7ed379a4050683e' 
  AND token = '2Ib4a9B67hpXawkSulzvPaR1i/MjCFTFC1hWL82W4S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}