SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55e3e7fa8f858375a868b46f6a1a8467ee70a107b58e3a56eb23be04e6fe93b6' 
  AND token = 'm/oa5Jbt7lnVZUj1UVf3V4jmXU84b8XrtP/cJ7xETUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}