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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a896c5cc732abfe215a79a1e36f7ef501254c7f25615ef2563ab781fec6979e1' 
  AND token = 'loP6v+IGE/MfLyqKH/L9JI2rb24n/8F6+K9fsTk0eu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}