SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0959d3a8760ae129b599c5c00df510e968125aefe10a8fbd32a09b4891543453' 
  AND token = 'i+/eJ5WTtEFo7T0/YKzCPnD6CuLBVpPHboOmbv9tpDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}