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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ec58e7847d1df790cb1037dcd42c705d88623a2345d14640b3c60c885673cd' 
  AND token = '4C9wGneOT3ecs5dks4ISxK5L/lZYEVdK11osx4T/6uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}