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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b5ae8649a397208d77b902d6606980ebdf99249d825e36c8514b8783b8ce44d' 
  AND token = 'TOxTTt07hgm7OZXnkgmkxUeiMrzhg2zmZH26D9WsGZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}