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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f1bdb754c31ba6e952bc7d5497a207fac476a2a8faf447a9978ceec3360fa0d' 
  AND token = 'Yu81Pwsr6P/W17o27Tt/POXpoXBaeVrW1K7Atmzlr6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}