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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20e36b7bf5f9034a28a91ed42da5d84260d144638da8ba9acc5b2eaae6ae549e' 
  AND token = 'KCEynXe09/EowHTEC+JmR5lO/V87SXoj3S5mpr1/nZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}