SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8e35f01fa46933c24851db4e1d560ab57a564da50d802c0d23b0dc87dd63e36' 
  AND token = 'HQbFZo/c0N/nx9q/kN8xyeu+w9KmB9O/HGMm5I59t6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}