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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3f2d2b2d8b02934fd6fb11f7098f7173d63b06d57bb65c7c24418ee84f806dc' 
  AND token = 'cVWY39KzX3Fkxf1V3hhNsTc52F4A9Z85+GiGPyyae/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}