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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f03335600d7ccb3b6c09cdcea937e3de36403a151e2dadca83b02f028e8b50f0' 
  AND token = 'kxe5rkEkTNnaxleRq023PkJK1H77j3nai5tZp86STSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}