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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5bd2755d7e8c23e61adbaf3fc97b165aa53b449cfc2f8146c97fdccd718bf39' 
  AND token = 'FQF5YVVDlKdKLBockQZ9VcKpnAhqM7QOiQeV8o+3dDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}