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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a95a7ec99983b5a3bf4d168c4b0533968740d03bdf265c5ec5b57623e9c948' 
  AND token = 'f9pvxnqvzVE58APgYQRREUj18dQsKXqI/IN7ahxk0Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}