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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '324df840d1c6e7c32e12a9427ad210c7248f22c27f71403d8a8b842af158fa24' 
  AND token = 'v4LekR4ZaB/0/L7vweK8yi3btVzSQxZ2pRTj8h6YWcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}