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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3f4b74c87cc879541a15fab89c6d96851f934b5a3efbe593cbb971e52c37756' 
  AND token = 'Xqv2oRXSX4/ADOL2w7LPO4sz4x7mzOCmCPaqGG2QwCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}