SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d4dc9c041773cdb621c907b92e31ccdfa43887faa66f85d9c098aed18349677' 
  AND token = '6cRrwO7zYiJSP4MYJEY80x5vPzEAP0GwmWWkq2dRIfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}