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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d795fc82e8629bec96ab52d79934ecda17f7fdeb26b02d2d6e1b6997e5c9e0' 
  AND token = '8GLeu7GOjayIa32v5dVOnFkD0gBacVzlIU6ljXshTv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}