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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a0f09d8e157cf612b24c91ef4d73a921a3caa2d085dbd5f2d730de9ab9292d8' 
  AND token = 'TsOS+JD3kn7m3MmORm6xFK7+WjDHeuTgBowQw0pRt58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}