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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '533f54f8b19b3531bc0a913af0809cd3e88de6b0e0b5383ed85d0fc5775c56e0' 
  AND token = 'eUMfTSUzV1oJTSrSwc3usr2sZhNI1aoqSg7gp2qGcW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}