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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4221ad6453eaf788bff8dbc098bd527f5ff8bf3b5045af740f1e1b383c8ad3d' 
  AND token = 'fo/vvA6lIToN37XquWuusaTEDVce0g+bhi7fDhJ/Bpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}