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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5962e17929460a0e289a30848b4fb5c63a63c804e1b9f85c64e4c01ae6d2b997' 
  AND token = 'ueOxHg7a2PZLBjlH3q0Q+l6lsFKvVNMwjNtK6T7C6iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}