SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f65296c9537cce209581d534a1736be70ad69c89a6544b4bfd6a95d8459f3ddb' 
  AND token = 'lMwi6pcpNF+8q0SlEfdz5LpWCb8ldj9wzqvvvEBqK8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}