SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e355c848c9465134691fa0fac246476a7154811e543b5845e178be151f95a1f4' 
  AND token = 'aWegeimT59+ZrS0RR76M/e8GjiO4SpnJgLoXmFiFuVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}