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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7075ef04bea9b6c62f48c47842e0c784d8c32804601325e98e96e48220feb6c' 
  AND token = 'eM8aLv90KpH6obnW5+gnGDZFibuuvQaKuYn7F2uuLoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}