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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fa73cb4050e1fffea5971eed823639a630911ddeca00a61adc3eba0e3e125b7' 
  AND token = 'Nxh9m1qdO17VvsfsAUQw8e05varkuctT+lX6F+87rWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}