SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be623e8eb8ea93323ea6227338dbd125c0b3bd17327006d035d3e37bc6460de7' 
  AND token = 'DS0hoozT1rAwAyxID3lyACrFBW54EnBDaVMylC5jd1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}