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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54f79d15b833f3f9b2c0926d9edc0549f883dcd3e2c61ada0cd106dc747c759d' 
  AND token = 'Ja+5dq07a4B6MkqzZgHxsoHerRD2V3tL6arFCqzx7B4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}