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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d24ac87a97669f2190608bffd76344cb047e832c8f16d4bed84e7df9166d796' 
  AND token = 'nOIbjcxo2ElRTna5PPozFJkJNKW9DFRYC4rZY1JBjHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}