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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3001821de69c849db7d141d92a522e913d5fb54fbadbdc9d71802bd69fed82e6' 
  AND token = 'QmlO1HjyaNTSm3dARcaNkQ4ixa+zgRyx0iigdA3et3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}