SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f0d552a047500d50afac01b089829a0d79e2a6aef0186a7b9eda20766a83e6' 
  AND token = 'TBm8Gp2yuIguxQ6YVn5SVTp2FAxrR/k+3Dv0E0ReX34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}