SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5335585bc1e4a46d107646a59b95a1f53ed0b43e770531006f0ba187b45f34b6' 
  AND token = '0H7T3yHDUzvsAWS8QxBNZdTHoXV+71omjm2AbbjNr3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}