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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5b3aec741fbaf8560b5364cce2797a94b91fe77fc1110b7664fdd54bd594513' 
  AND token = 'YWUIcud/VYX0J244o93sPLowFrV51aKtT0uNlq+R4Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}