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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aadcf360a2ffa0ac459be4c0ad9cf5278545862244166eba30de18ba472fad4' 
  AND token = '/2RWAaOJbA8GIcimqmDhFh98BgvEiIQ9WzrPKzMuQIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}