SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a0de0b1ac5322b1b7f49d4113604e461fb650b44b406891b57e904a89f1081' 
  AND token = 'yXeWe+pCgLnj0O7knIAJh00FPas9dvEn4Sb0rOjUqQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}